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Cancer Care @ Humber River Hospital & North York Medical Building @ 1017 Wilson Avenue – Toronto

Cancer Clinic #205 @ 1017 Wilson Ave.,

Clinic 205: Oncology & Hematology, Dr Jonathan Wilson; 416-249-4367; fax 416-249-9433

Clinic 305: Oncology & Uro-Oncology, Dr Sharon Sharir;

 

cancer clinic

Humber River Hospital (HRH) has a well-established Cancer Care program. Our Integrated Cancer Care Program consists of members from other clinical programs such as Diagnostic Imaging, Endoscopy, General Medicine, Mental Health, Pharmacy, Palliative Care, and Surgery. HRH has a large Cancer Care Outpatient Clinic for chemotherapy treatments, and actively participates in Oncology clinical trials. Humber River Hospital was the first community hospital in Ontario to participate in these clinical trials.

HRH partners with tertiary cancer centres and other academic centres such as Sunnybrook Health Sciences Centre and the Odette Cancer Centre, the Princess Margaret Hospital Cancer Centre, Mount Sinai Hospital, St. Michael’s Hospital, and Southlake Hospital’s Stronach Regional Cancer Centre. We also partner with community cancer support agencies such as WellSpring, Canadian Cancer Society, and Community Care Access Centres (CCAC).

Our cancer team provides a full range of support to patients who are living with cancer, at all phases of their cancer experience – consultation, diagnosis, treatment, follow-up, and palliative and supportive care. The team is actively involved in initiatives set by Cancer Care Ontario and the Central LHIN Regional Cancer Program. Many of our team members have leadership roles within provincial, regional, and local Cancer Care committees.

Resource information about cancer and our program can be found on our Patient Publications page.

Our Program has a 30 bed inpatient oncology unit that includes a radiation isolation room for the treatment of Thyroid Cancer. We also provide inpatient pain and symptom management support.

Our Cancer and Oncology Clinic has 28 systemic and supportive treatment spaces. Our specialized cancer care team provides systemic therapy treatments which include intravenous chemotherapy and oral therapies, and also offer follow up care including supportive care for cancer related pain and other symptoms.

CANCER IS A DISEASE OF COMPROMISED IMMUNITY

“Cancer is a Disease of Compromised Immunity.  Systemic Total Body Detoxification is a required cleansing process for a healthy life style and crucially necessary in order to increase the body’s immunity before, during and after any type of cancer treatment.”

Marcel M. Cohen, ME, P.Eng.,
Basics of the Immune System

The immune system is a system of many biological structures and processes within an organism that protects against disease.
To function properly, an immune system must be able to recognize the native cells of its host as ‘self’, and therefore, distinguish them from all abnormal or foreign cells and structures which gain access to, or are present in the body, in order to stage appropriate defensive maneuvers. These foreign structures include all types of infecting pathogens as well as cancerous tumor cells.
The immune system comprises multiple organs, including the spleen, bone marrow, and thymus. However, elements of the immune system are present in all tissues, such as Kupffer cells (immobilized macrophages) which line the sinusoids of the liver, or Langerhans cells, immune cells interspersed among the keratinocytes of the skin.

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The immune system consists of many different types of cells:

  • B-cells
  • T-cells
  • Natural killer cells
  • Eosinophils
  • Dendritic cells
  • Granulocytes
  • Monocytes /Macrophages
  • Basophils
  • Neutrophils
  • Innate lymphoid cells
  • Red blood cells
  • Thymocytes

There are 2 different type of immunity:

  • Innate Immunity (non-specific immunity)
  • Adaptive Immunity (specific or acquired immunity)

Innate immunity involves a number of broad functions:

  • Recruitment of immune cells to an infection site through production of chemical factors or mediators (cytokines) at the damage site
  • The complement cascade is activated, which identifies pathogens, activates immune cells, promotes clearance of antibody complexes and dead cells
  • Identifies and removes foreign substances in tissues, organs, lymph and blood, via specialized white blood cells
  • Activated the adaptive immune system via the process of Antigen Presentation
  • Acts as a physical barrier (epithelium) against infectious agents

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Adaptive or acquired immunity takes advantage of the immune system’s ability to demonstrate memory once exposed to a pathogen which has specific identifying markers associated with it. Initial exposure will require a much longer period of time by your body to eliminate the invaders (approximately 4-8 days, or longer depending on the condition of the immune system and other factors). The second attempt by identical invading pathogens will involve much swifter processing by your immune system, and the host may not even know that there was an infection present. This is the basis behind the immunization process, and the properties of memory, which the adaptive aspect of the immune system possesses.immune-1

 

Optimizing the immune system is crucial and a must in maintaining a DISEASE FREE LONG LIFE. It is common knowledge that a weakened immune system leaves the host vulnerable to infection, and to other diseases including cancer. Cancer is a disease of Compromised Immunity.

An opportunistic infection is an infection caused by a pathogen which takes advantage of a host with a weakened or compromised immune system (or an altered microbiota, such as a diminished gut flora, post treatment with antibiotics). Many of these pathogens do not cause disease in a healthy host who has a normal immune system. Often, gut flora cannot be restored by the body to its prior levels before the use of antibiotics. Simply, antibiotics compromise body’s immunity. Prolonged use of antibiotics reduces the body’s inherent immunity as such increases the risk of cancer.

The same pattern can be described of tumor formation. Therefore, it can be restated, that an optimized (or amplified) immune system must be capable of destroying invading pathogens as well as suppressing the development of tumors in its host, and will continue to do so, as long as the health of the immune system is maintained.

So how do we optimize and maintain the health of our immune system?

We start with an aggressive detoxification process named “Rerum Detox Protocol” and we maintain a toxin free life style.
And especially we adopt Exitotoxins free life style which deteriorate our brains. For example at all cost we avoid Glutamate of MSG (Mono Sodium Glutamate) which destroys brain cells.

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Detoxification

Detoxification is a set of processes which clears the body of accumulated, harmful immune-2chemicals and effects, which are broadly referred to as toxins. This is done by removing impurities from the blood in the liver, where toxins are taken, and processed for elimination. The body eliminates toxins through the kidneys, intestines, lungs, lymph and skin. All six parts must perform impeccably to detox the body.

However, when this system is compromised, impurities aren’t properly filtered and will accumulate. Every cell in the body is adversely affected. Hence the start of compromising body’s immunity.

There are innumerable impurities found in food, water and air. Radiation and stress also have adverse effects. In food, many chemicals which we intend to consume, such as ethanol, are considered toxins, but there are other chemicals such as preservatives, dyes, flavorings, antibiotics, hormones, pesticides and various pollutants, which find their way into our bodies through the foods we consume, which must be considered as harsh toxins for the immunity.

Today, with more toxins in the environment than ever, it’s critical to detox, for symptoms such as:immune-3

  • Unexplained fatigue
  • Sluggish elimination
  • Skin irritation
  • Allergies
  • Low-grade infections
  • Periorbital puffiness (eye bags)
  • Bloating
  • Menstrual problems
  • Mental confusion

A detox program can help to cleanse the body by:

  1. Resting the organs through fasting or drinking a strategic meal substitute
  2. Stimulating the liver to drive toxins from the body
  3. Promoting elimination through the intestines, kidneys, lungs and skin
  4. Improving circulation of blood
  5. Refueling the body with healthy nutrients

Nutritionists will recommend that we should detox at least once a year. immune-4At Rerum North America, we recommend that many elements of a strategic detox plan remain in effect daily. However, caution should be exercised in the case of nursing mothers, children, and patients with certain diseases.

How do you start detoxification?

First, lighten your toxin load. Try to Eliminate:

  • Alcohol
  • Coffee
  • Cigarettes
  • Refined sugars
  • Processed foods
  • Carbohydrates (during ketogenic diet cycle);

These act as toxins in the body and are obstacles to your healing process. Also, eliminate or minimize use of chemical-based household cleaners (especially in aerosol format).

immune-5Another deterrent to good health is stress, which triggers your body to release stress hormones into your system. In large amounts they create  toxins, slow down detox enzymes in the liver, and suppress the immune system. Exercise, yoga and meditation are simple and effective ways to relieve stress.

So, you have started by limiting the ingestion of ‘social toxins’, and you have taken steps to reduce stress, and the damage which occurs as a result. Let’s move onto the issue of detoxifying the body and optimizing the immune system.

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DETOXIFICATION

For Our Cancer patients and those who are not diagnosed with any disease but interested in Disease Free Long Life we provide an Intensive Detox Process based on a demanding schedule; that is a continuous detox process lasting three weeks, every day of the week, five-hour long detox sessions, lasting actually until the body is entirely free of toxins. This is based on our Proprietary Rerum Detox Protocol and Rerum Detox Processes.  For more information, submit your information blow.

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In addition, for our Cancer patients and those who are not diagnosed with any disease and interested in Disease Free Long Life we provide a Proprietary Diet Process based on Rerum Ketogenic Diet.

As well we provide proprietary Detoxification process, Modified Ketogenic Diet, Rerum Dietary Supplement, Specialized Probiotics and Supplements for couples planning to have a family.

What follows are generic Detoxification Processes One can follow.

 

  1. Exercise – cardio, resistance training, jump-roping are all good. They increase sweat to remove toxins, and reduce stress, thereby improving immune strength.immune-18

Exercise is an essential part of a healthy lifestyle. Exercising helps to reduce body fat, and to get rid of toxins through perspiration. Exercise also helps with digestion, circulation, organ health and function.

If you opt to make exercise a regular function in your life, then you can assist the body in the cleansing process on a regular basis. So sweat it out at the gym, not only because it makes you feel good and releases the best.immune-11

A good form of exercise, helps to meditate and reduces stress, which results in a decrease in the release of some harmful hormones, such as cortisol, which is a corticosteroid produced in the adrenal cortex. Cortisol is released in response to stress and /or low blood-glucose concentration. It increases blood sugars through gluconeogenesis, a metabolic pathway which generates glucose from non-carbohydrate substrates (some amino acids, glycerol, lactate, pyruvate).  Cortisol also suppresses the immune system, and decreases bone mineralization.

Exercise and a positive general outlook are 2 methods of minimizing stress and the presence of stress hormones in the blood. Stress can result in weight gain, poorly functioning immune system which increases risk of infections, cancer and other illnesses, and a complete lack of energy.

 

  1. Detox drink recipes can assist in ridding your body of toxins and bringing it back into healthy balance. There are many of these, such as:

Lemon cleanse     immune-12       

Lemon consists of ascorbic acid, vitamin C, elevates glutathione and assists in the cleansing process.

2 tablespoons of freshly squeezed lemon juice, 2 teaspoons of pure maple syrup and one-tenth teaspoon of cayenne pepper in 8 ounces of water.

Dandelion teaimmune-7

Dandelions are a great source of vitamin A, potassium, iron and calcium. Dandelion detox tea is a diuretic that will eliminate bodily toxins through your liver and kidneys.

4 tablespoons of fresh dandelion per cups of boiling water. Let brew 10 min.

Cranberry juiceimmune-15

According to Mayo Clinic, there is some evidence to suggest that drinking cranberry juice may help prevent urinary tract infections and ulcers in healthy individuals. Cranberry juice also contains vitamin C, manganese and antioxidants. Cranberry juice is a commonly used for detoxification.

These are only a few example of the hundreds of drinks which can represent a one-meal substitute during a detox program. Most of the detox elements outlined, can be maintained on a daily basis. By optimizing the removal of wastes and management of stress on a day to day basis, the immune system strength will be maximized.

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Here are some recommendations to ensure that, moving forward, your toxins will not get out of control:

  1. Use organic foods:immune-13

Minimizes the ingestion of pesticides, preservatives, antibiotics, hormones, and other toxins.

  1. Have regular, intense massages:immune-14

It is a good way of detoxifying the body, an intense deep tissue massage that focuses greatly on the pressure points within the body.

 

  1. Drink far more water:immune-16

2-3 liters per day at minimum, will flush out your system naturally and  routinely, contributing to clearer skin, properly functioning organs, and a more effective circulatory, respiratory, and digestive system.

 

  1. Replace coffee with green tea:

A little caffeine is okay, and green tea contains important antioxidants that our body needs. It helps to naturally detoxify and supplies some important  anti-cancer factors.

 

  1. Acupuncture:

Acupuncture helps to naturally heal many health problems, while also helping you to cleanse blockages of toxins in the body. This holistic approach been around for centuries and is an excellent cleansing method.

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  1. Eat more fiber:       immune-20                 

Fiber chelates bile, which is a substance produced by your liver, which is stored in the gallbladder until needed. Bile is an emulsifier for rich, fatty food. Removal if bile in the GI tract by dietary fiber, forces your liver to extract cholesterol from the blood (reduces blood cholesterol levels) to replace the lost bile. Fiber also pulls water from the blood stream (reduces blood volume and thus blood pressure) and provides nutrients for gut flora in the colon. These bacteria digest the nutrients to produce small chain fatty acids which help to reduce polyp development in the colon, and therefore, decrease the risk of colorectal cancer. Fiber also helps to loosen toxins and solids which remain in the GI tract. It allows rapid elimination, again reducing the risk of toxic reactions with the endothelium of the gut, and the risk of cancer.

 

  1. Sufficient sleep:immune-21

Without proper sleep you can gain weight, you will have a compromised immune system, and of course you lack natural energy. The body wears down, and you get sick more easily. 

 

  1. Avoid obvious environmental toxins:immune-22

Avoid smog, diminished air quality, second hand smoke and industrial fumes as much as possible.

 

  1. Turn to probiotics to get rid of the bad bacteria and welcome in the good This complements fiber to ensure the content of flora is optimal, and the bad microbes are eradicated.immune-23

 

  1. Learn to incorporate superfoods into each meal:

Superfoods contain important nutrients and antioxidants which our bodies need to fight off infections, cancers and harmful toxins and substances that may compromise our immune system and our overall health.

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Superfoods are a delicious and nutritious group of foods including foods rich in omega-3 fatty acids, and antioxidants, like:

Salmon, Tuna, Avocado, Walnuts, Almonds, Olive Oil, Flax Seeds, Blueberries, Raspberries, Spinach, Kale, Tomatoes

Some of the herbs that offer great cleansing in the body include: Dandelion, Turmeric, Milk Thistle, Cypress, Hydrangea Root, Gravel Root, Garlic, Onion, basil

 

  1. Cut out simple carbohydrates, white sugar and flour:immune-27

Rice, pasta, bread, potatoes and any simple sugar need to be out now! Consequences of starches and simple sugars are a major component of the very toxins that build up in your digestive system, for which detoxification is required.

 

  1. Turn to home remedies to treat illness rather than antibiotics:

Antibiotics contribute to toxins in the body, kills off normal flora and weakens the immune system, which will pave the way for opportunistic pathogens and drug resistant organisms to enter your gut, proliferate, and produce toxins.

  1. Use ginger, garlic, other natural herbs which will speed up recovery by enhancing natural defense mechanisms.

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Garlic contains multiple active compounds and minerals which have a positive effect on the body. Those will only be listed here – please follow the in-depth discussion on Garlic and Its Properties – For a Disease Free Long Life, which will follow in 2016.

Garlic contains innumerable active ingredients and trace minerals:

Allicin, Allicinase, Ajoene, Diallyl disulphide, S-Allylcysteine, Thiacremonone, Copper, Iron, Zinc, Tin, Calcium, Manganese, Aluminium, Germanium, Selenium,

Therefore, garlic exhibits many properties:immune-28

Natural antibiotic properties; Anti-viral and anti-fungal; Anti-cancer, especially stomach, colon, esophageal, pancreatic and breast cancers; Prevents cancer-causing agents from binding to cells in the human breast; Produces h2s (hydrogen sulfide) in the body which attacks breast, prostate and colon cancers; 12% reduction in blood cholesterol levels; Detoxifies the body by stimulating the liver to produce more detox enzymes; Strengthens the immune system; An effective anticoagulant; Reduces allergic airway inflammation; Has anti-arthritic properties; Reduces the inflammatory aspects of obesity

 

  1. Other natural foods which provide natural infection control:immune-29
  • Coconut oil – MCT has antibacterial properties
  • Ginger – contains gingerol, which fights infections in the mouth mainly
  • Lemons – contains 2 compounds, coumarin and tetrazine, which fight a number of pathogens
  • Horseradish – fights infections of the urinary tract and the lungs
  • Turmeric (Curcumin) – fights infections involving many Bacillus species, S. aureus,  E. coli, P. aeruginosa

     17.  Probiotics

  • Found in yogurt, capsules, fermented foods – fight infections at the GI tract level
  • A Suggested Brand: Bravo Probiotic found at online shop at this web site.

For Information and Ordering Bravo Probiotics please sign up below

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At Rerum Wellness, our supplements are designed not only to optimize your immune system, but to amplify the response of that system by at least an order of magnitude. Detoxification, infection control, disease control, treatment of clots, deep vein thrombosis, decreasing risk of embolic events, reduction of multiple cranial problems, and many other benefits, need not be left to chance.

Inquire about our fourth generation supplements and our complete line of wellness packages which are treatment solutions for the above mentioned ailments, or for the healthy individuals who want to improve their health towards Disease Free Long Life.

To Order Rerum:

For Information and Ordering Rerum please sign up below

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Article Credit: Senior Writer, Andre Sabongui, M.Sc., RDCS, RDMS

North York Medical Building

 

 

Rerum® Protocol North America

The ultimate Macrophage Activating Factor (MAF)
All natural Dietary Supplement well above and beyond blood-derived GcMAF!

Rerum Protocol For Disease Free Long Life North America

Rerum®is Macrophage Activating Factor (MAF)

Strengthening the “Innate Immune System”

Click here to Order Rerum

 

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Expression and Function of Macrophages

Which Are Activated by Rerum®

Rerum Protocol For Disease Free Long Life North America

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Rerum®is Macrophage Activating Factor (MAF)

Strengthening the “Innate Immune System”

Inventor, Prof. Dr. Marco Ruggiero

MD, Clinical Radiology; PhD, Molecular Biology

  • The Science: A number of other research groups, have discovered that there are different phenotypes in humans, thus leading to different coding regions for amino acids for the human Vitamin-D binding protein (DBP). This is due to allelic differences: one group of GC polymorphism, the GC1 group, has a threonine residue whilst the GC2 group has a lysine residue.
  • The possible genetic alternatives in GC1 and GC2 groups on the same genetic locus lead to completely new conclusions being drawn about GcMAF being the only protein-derived MAF (DBP) in healthy human bodies. If there are humans without a threonine coding for GcMAF, in other words subjects homozygous for GC2 and therefore with a lysine coding instead, they would not have a single molecule of GcMAF in their bodies; therefore, their immune system would be weak and they would have a much higher risk of developing cancer. But this is not the case.
  • On the other hand, studies around the world by many researchers have demonstrated, amongst other things, that the activation of macrophages produces pro-immunogenic, anti-inflammatory, neuro-protective and even anti-cancer/anti-angiogenetic effects.
  • The efficiency of such an immune modulation is based on the molecular structure of GcMAF, which contains vitamin D and fatty acids, in particular oleic acid and chondroitin sulfate. The effects observed in GcMAF are solely due to its function as a carrier protein. The GcProtein itself has no effect per se; it only serves to carry the molecules endowed with all the effects erroneously attributed to GcMAF.
  • And what about oleic acid and vitamin D? Could other effects previously and erroneously attributed to GcMAF be due to vitamin D and oleic acid instead? Indeed, numerous studies now show the benefits of these substances in different diseases.
  • Based on this new understanding our 4th., generation “Dietary Supplement” has been reconstituted based on all the effects described and even boost the power of the aforementioned structure by designing the proper Macrophage Activating Factor: as Rerum®. This is a new generation MAF without the GcMAF protein itself. In the newly developed Rerum®, the protein backbone is replaced by chondroitin sulfate.
  • While GcMAF from human blood protein only has one chemical bond for certain moieties, chondroitin has more than 50 moieties for N-Acetylgalctosamine (GalNac). Rerum® demonstrates the effects attributed to GcMAF, and even goes so far as to also show those properties that have long been linked to chondroitin sulfate.

 

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  • What is Different?
  • Rerum® is not derived from blood and therefore not affected by any of the problems afflicting blood-derived  proteins.
  • Rerum® is not digested by stomach acid or by stomach proteases since it is not a protein; on the contrary, its bioavailability is increased by digestion.  
  • Rerum® does not require any particular care for storage and shipping, such as special cooling or even freezing.  
  • Rerum® does not induce allergic reactions since glycosaminoglycans are notoriously non-allergenic.  
  • Rerum® is a bona fide dietary supplement since it is composed of well-known dietary supplements that have been in use for decades.  
  • Rerum® is inherently safe since it is composed of components that have been used for decades in human medicine. Chondroitin sulfate, vitamin D and oleic acid are regulated substances in the U.S. as dietary supplements, approved by the Food and Drug Administration.  
  • In Europe, chondroitin sulfate formulations are approved as drugs with evidenced efficacy and safety demonstrated by clinical trials.  
  • Rerum® is extremely bioavailable at variance with long proteins such as GcMAF.   This is due to the inherent flexibility of the chondroitin sulfate backbone and the presence of a fatty acid, oleic acid.   Thanks to this unique combination, Rerum® is rapidly absorbed via a variety of routes and is immediately bioavailable.  
  • Rerum® is nanosized.   This means that its contact surface is about 1,000 times wider than that of a long protein such as GcMAF.   Rerum® is therefore able to reach a much larger number of targets in the human body.  
  • With the invention of Rerum®, we finally have the one and only, real, safe Macrophage Activating Factor (MAF).  
  • Rerum® is manufactured in a state-of-the art GMP-certified facility in Germany. Rerum® is available in sterile vials for oral intake (alternative: adapplicator).
  • Rerum® is in the process for approval by Health Canada and FDA in the USA.
  • Rerum® shall be shipment ready by early 2016. As well it will also be available for administration to patients as part of Health & Wellness treatment and protocols at our facilities in Toronto at our Integrative Health Center North America with boots on the ground across the USA, Hawaii, Puerto Rico, and Mexico.

 

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Rerum® is Macrophage Activating Factor (MAF)

Strengthening the “Innate Immune System”

Integrative Health Center North America

Canada – USA – Europe

Rerum Protocol For Disease Free Long Life North America

 

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GENETICS AND NATURAL WELLNESS

The human body is a very complex structure, made up of many different systems which work together to manage its over 37 trillion cells. In each individual cell, resides a complete copy of the human genome, with all the information necessary to run the entire body. If stretched out, one copy of human genome measures 2m in length, and the DNA of an average adult would stretch to the moon and back.

The human genome is the complete set of nucleic acid sequences, encoded as DNA, within the 23 chromosome pairs in all cell nuclei, along with a small DNA molecule found within cellular mitochondria. One set of chromosomes of an individual originates from each parent.

In reproduction, gametes are formed, which are cells containing only 1 set of chromosomes (23 chromosomes, no pairings). In the process of meiosis, the preparation of sex cells, mixing of our chromosome pairs occur, so that the set of genes which are represented in our germ cells (ova or sperm) are a mixture of the genotypes of both parents. Such mixing occurs through the formation of chiasmata.

 Genetics North York MedicalIn 1984, the American government planned and fully funded an initiative called the Human Genome Project, in which 20-25 major university centres from the United States, the United Kingdom, Japan, France, Germany, and China collaborated, in an effort to elucidate the sequence of the entire human genome, including multiple variations which may occur in any one gene. This required the sequencing of over 3 billion DNA nucleotides, and took nearly 14 years to complete, ending in 2003, at a cost to the U.S. taxpayer of more than $2.7 billion.

Genetics North York Medical

Moving forward from 2003, genome-based research has enabled medical science to develop highly effective diagnostic tools, to better understand the health needs of people, based on their individual genetic make-ups, with hope to design new and highly effective treatments for many diseases.

Genetics North York Medical

Today, an individual can walk into a genetics testing centre and have a DNA profile done, to learn about their risk of many diseases, and some cancers. Approximately 80% of cancers are linked to pollutants (chemical carcinogens) in the air, food and water, as well as radiation. The other 20% may be linked to genes which normally regulate cell growth and proliferation (proto-oncogenes), and under abnormal conditions, may be mutated into oncogenes, causing cell division at an accelerated rate, resulting in tumor growth.

Genetics North York Medical

Oncogenes were first identified in 1970 at the University of California, and were linked to a retrovirus. In 2002, the World Health Organization’s International Agency for Research in Cancer, estimated that 18% of human cancers were caused by infection, with 12% being caused by one of seven viruses (tumor viruses).

Genetics North York Medical

Retroviruses, such as HIV, are RNA (some retroviruses can carry DNA) carrying viruses which can infect a cell, use the cell’s machinery to produce corresponding DNA through reverse transcription, then produce biochemicals which allow its newly produced DNA to insert into the genome of the cell, and finally cause the cell to replicate the viral DNA code into many new retroviruses.

Tumor viruses come in different forms: DNA-carrying viruses, such as adenovirus, and RNA-carrying viruses, such as the Hepatitis C virus, which can cause cancers, as can retroviruses having either DNA or RNA genomes (Human T-lymphotropic virus and Hepatitis B virus).

Often, tumor viruses do not cause cancer in their hosts. For example, adenovirus does not cause cancer in humans but is instead responsible for conjunctivitis, colds and other acute illnesses. They only become tumorigenic when infected into certain rodent species, such as Syrian hamsters. Some viruses are tumorigenic when they infect a cell and persist in that cell as circular episomes or plasmids, replicating separately from host cell DNA (Epstein-Barr virus and Kaposi’s Sarcoma-associates herpes virus). Other viruses are only carcinogenic when they integrate into the host cell genome, such as polyomaviruses and papillomaviruses.

Genetics North York Medical

A direct oncogenic viral mechanism involves either insertion of additional viral oncogenic genes into the host cell or to enhance already existing oncogenic genes (proto-oncogenes) in the genome. Indirect viral oncogenicity involves chronic nonspecific inflammation occurring over decades of infection, as is the case for Hepatitis C virus-induced liver cancer.

These two mechanisms differ in their biology and epidemiology: direct tumor viruses must have at least one virus copy in every tumor cell, expressing at least one protein or RNA that is causing the cell to become cancerous. Because foreign virus antigens are expressed in these tumors, persons who are immunosuppressed such as AIDS or transplant patients are at higher risk for these types of cancers. Indirect tumor viruses, on the other hand, can be lost from a mature tumor that has accumulated sufficient mutations and growth conditions (hyperplasia) from the chronic inflammation of viral infection. In this latter case, it is controversial but at least theoretically possible that an indirect tumor virus could undergo hit-and-run, and so the virus would be lost from the clinically diagnosed tumor. In practical terms, this is an uncommon occurrence if it does occur.

Genetics North York Medical

So, now that your DNA report is ready, and there are no emergencies, the findings can be stored away. But what if there was some bad news, such as a high risk of multiple forms of cancer? What can you do with that information? If the cancer is not yet present, most people would worry, but they would do absolutely nothing.

Could we change our lifestyle? Yes, but how would that overcome the risks which are inscribed in our blueprints? Well, regular exercise is a start, but it is unlikely to be enough.

Should we wait until the tumor presents itself, hope to catch it early and plan for the burden of chemotherapy or radiation therapy? Has it presented already, but we simply have not noticed? In allopathic medicine, the use of chemotherapy for the treatment of cancer is done so with great uncertainty, and with the hope that the drug kills the cancer before killing its host. Is this the basket where all our eggs should be? Do we even have a choice? Absolutely!

 

Credit: Article Editing by Andre Sabungui -North York Medical Building

Rerum Ketogenic Diet

DISEASE PREVENTATIVE KETOGENIC DIET

We have re-designed the Ketogenic Diet to slow the progression of disease. Any disease, for those who are diagnosed and to immunize the body against disease, any disease, for those who are not diagnosed. Modified Ketogenic Diet implemented accurately can produce optimum results by way of weight loss, increased energy, and increased body immunity against disease, any disease.   Modified Ketogenic Diet supported by proprietary supplements such as Bravo Probiotics cause the human body cells operate at optimum levels where such an environment is not conducive for any disease from taking hold in the body.

When we look to a diet for answers, any diet,  it usually has to do with a desire to lose some weight, and to look and feel better about ourselves and the image we portray.

Rerum Ketogenic DietBut which diet should we follow, and much more importantly, why? Does the explanation associated with a particular diet make sense? Is there evidence-based research or clinical trials in the medical community to support this or that dietary strategy?

There are thousands of diets, most of which pivot of a reduced caloric intake, and pay little attention to anything else. What about vitamins (vital amines), essential amino acids and trace minerals, all of which the body cannot produce on its own, and needs your help to supply, through diet. Without these in reasonable quantity, serious injury and even death can result.

In history, many different diets have evolved, in which vitamin C, ascorbic acid) had been neglected. According to Linus Pauling (and more recently, the medical community at large), 2 time Nobel prize winner (one for peace, and the other in chemistry for the development of the electronegativity chart of the elements), vitamin C is a powerful anti-oxidant, which, if taken in mega doses, can significantly reduce the incidence of cancer through its activity on free radicals in the body.

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Rerum Ketogenic Diet

However, among many other roles of ascorbic acid, the most important is its involvement as a cofactor in the production and strengthening of collagen.

Collagen is the most abundant protein in the human body. It is a protein composed of 1042 amino acids, and is arranged in a triple helix, which is thoroughly cross-linked for strength. Essentially, it represents the scaffolding which holds the whole body together.

It is found in the bones, muscles, skin, tendons and blood vessels, and provides strength and structure.

Rerum Ketogenic Diet

One of the amino acids in the structure of collagen is Proline. In most cases, the proline residue must be hydroxylated, in order that further hydrogen bonding can occur with the neighboring chains. This hydroxylation is catalyzed by an enzyme called prolyl hydroxylase, and ascorbic acid is a cofactor in this reaction. Without vitamin C, in fact, this reaction cannot occur, and the added inter-chain hydrogen bonds will not develop, causing the collagen fibers being produced to be defective.

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Rerum Ketogenic Diet

In fact, collagen synthesized in absence of vitamin C will denature at 24oc, instead of the 39oc in normal collagen. Since humans have a normal core temperature of 37oc, this poses a real problem. Bones become brittle, joints faulty, blood vessels unable to hold blood, skin ulcerates, teeth can no longer be held and will fall out, and ultimately, if not rectified, death will ensue. The lack of structural integrity of collagen in situ, is the basis of a disease called Scurvy, which, thankfully, is seldom seen any longer.

 

EAT FAT -YOU MUST EAT FAT

Until very recently, food biochemistry has been quite a mystery, even for physicians. Some generalizations have been made – ‘don’t eat saturated fats… they are not good for you’. This made sense for a physician, and it seems to make sense for most of us. There is some evidence to support a claim like this, but with the incomplete understanding of what happens to a chemical when it enters the GI tract, and the limited knowledge of cross reactions in the body, can we claim with absolute confidence, that consumption of a saturated fat is detrimental to our health. Perhaps saturated fat is harmful in the presence of other nutritional chemicals, and is, in fact, very good for us in the absence of that other nutrient. Perhaps backing up a little to look at the bigger picture might help.

The Rerum Diet is a high fat, moderate protein diet which involves no carbs, adequate supplements and a lot of water. In this diet, fish, fish oils, poultry, some red meats, butter, eggs, cheese, avocados, coconut oil, MCT oils, sausages, and some types of nuts (low quantity) and occasionally tofu, are some examples of foods which are in keeping with this diet.

Rerum Ketogenic Diet

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Per Marcel M. Cohen, P.Eng., (Canada) the originator of No Carbs Rerum Diet where the key is the lack of carbs – no carbs! To understand the basis of this approach, a few basics of metabolism need to be reviewed.

Any carbohydrate which is ingested, will be broken down through various means into their basic subunits, glucose, once absorbed and brought into cells, will undergo conversion, through glycolysis and the Krebs cycle, to produce an abundance of adenosine tri-phosphate (ATP), a high energy molecule which is the usable currency of energy in our bodies. But, if the energy is not utilized, it must be stored.

Glucose is a hydrophilic molecule. Storing glucose in general is difficult because of its water solubility and its relatively low energy properties (4 calories per gram carbs) compared with fat (9 calories per gram), and would require a large amount of space. Therefore, unused energy is converted into fat through lipogenesis.

Rerum Ketogenic Diet

Figure 1 – Excess calories convert into fat

 

Decades later in life, we may decide that a bit too much fat has been stored, and something must be done to shed those unwanted pounds.

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In the absence of carbohydrates, the body is forced to use alternative sources of fuel in order to produce ATP. The Rerum diet, which encourages the use of high fat (certain types) and proteins, causes our metabolism to shift in favour of ketosis.

Ketosis refers to a metabolic state in the body where there is not enough glucose available to use as energy, so a switch occurs where molecules called ketones are generated during fat metabolism, and used for most of the body’s energy. Ketones can be used for energy, and have a special property – they can be used instead of glucose for most of the energy needed in the brain, where fatty acids can’t be used. Also, many tissues of the body prefer to use ketones, in that they will use them as their primary source of fuel when available (myocardium for example).

Ketone bodies are formed by ketogenesis in the absence of glucose and when liver glycogen stores are depleted (or from metabolizing medium-chain triglycerides). The main ketone bodies used for energy are acetoacetate and β-hydroxybutyrate, and the levels of ketone bodies are regulated mainly by insulin and glucagon. Most cells in the body can use both glucose and ketone bodies for fuel, and during ketosis, free fatty acids and glucose synthesis (gluconeogenesis) fuel the remainder.

Longer-term ketosis may result from fasting or staying on a no carb diet, and deliberately induced ketosis serves as a medical intervention for uncontrollable epilepsy, and has shown success with other neurological conditions.

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In glycolysis, higher levels of insulin promote storage of body fat and block the release of fat from adipose tissues, while in ketosis, fat reserves are readily released and consumed. For this reason, ketosis is often referred to as the body’s fat burning mode. This is the advantage of the Rerum Diet.

The fact is, in a diet rich in carbs, stored fat will be much more difficult to release, if not impossible in many circumstances. Using our diet, even for general health, I unintentionally lost 16 pounds (my BMI of 27 is at the borderline, and I had not intended to lose weight) in less 2 weeks. Incidentally, I have also had environmental allergies for the past 28 years, which have completely disappeared in my first week on the Rerum Diet.

But are there any other benefits to the Rerum Diet?  Absolutely.

Research shows glucose fuels and even causes cancer cells. For greater clarity,

  1. Scientists have actually shown in the Journal of Clinical Investigation January 2014, glucose can cause cancer via not one, but two biochemical pathways2. There are at least six research studies in the last few years which show that:
    a. People with the highest levels of blood glucose develop more cancers
    b. People with cancer, who also have the highest blood levels of glucose, survive least.
  2. Johns Hopkins scientists have shown starving patients of sugar is crucial in colorectal cancer.
  3. A June 2013 paper in the European Journal of Clinical Nutrition listed the following conditions as possibly being helped by ketogenic diets:

Strong Evidence

Emerging Evidence (some evidence with more research in progress)

  • Neurological Diseases other than epilepsy, including Parkinson’s Disease, Alzheimer’s Disease, narcolepsy, brain trauma, and amyotrophic lateral sclerosis
  • Polycystic Ovarian Syndrome
  • Acne
  • Some types of cancer (especially, some types of brain cancer)
  • Autism

Rerum Ketogenic Diet

Swedish Study Shows More Cancer in People With Higher Blood Sugar, Regardless of Diabetes
WebMD Health News

Feb. 27, 2007 — Women with high blood sugar may be more likely to develop cancer, even if they don’t have diabetes, a Swedish study shows.

High blood sugar (hyperglycemia) wasn’t tied to men’s overall cancer risk.

But when researchers looked at specific types of cancer, they found that both men and women with the highest blood sugar levels were more likely to have pancreatic cancer, urinary tract cancer, and malignant melanoma (the most deadly type of skin cancer) than those with the lowest blood sugar levels.

Keeping blood sugar levels within the normal range may reduce cancer risk, write the researchers, who included Par Stattin, MD, PhD, of Sweden’s Umea University Hospital.

For the study, Stattin’s team conducted a study of 64,600 non-smoker, non-diabetic residents in northern Sweden when they were 40, 50, or 60 years of age.

Upon enrolling, the participants underwent fasting glucose and glucose tolerance tests, with 85% and 92% normal respectively.

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Study’s Results

The researchers followed participants for eight years, on average.

Overall, women with the highest blood sugar levels upon joining the study were more likely to be diagnosed with cancer before its end, compared with women with the lowest blood sugar levels.

Also, endometrial carcinoma (endometrial cancer) was more common in women with the highest blood sugar levels, compared with those with the lowest blood sugar levels.

Breast cancer was more common for women younger than 49 with high blood sugar levels, compared with those with the lowest blood sugar levels, the study also shows.

The results held when researchers considered other factors, such as participants’ weight and age.

Their study appears in the March, 2007 edition of Diabetes Care

In summary, the Rerum Diet is safe, it forces an alternate metabolic pathway to energy production that the vast majority of cell in the body can use, while allowing fat stores to be mobilized and weight to be lost confidently. Rerum Diet contributes to many other ailments as illustrated.

Please look for upcoming reports on Rerum Protocol and the Immune System.

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